Enzyme-linked immunosorbent assays utilizing virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections.
The latest outbreaks of Zika virus (ZIKV) in flavivirus-endemic areas spotlight the necessity for delicate and particular serological exams. Beforehand we and others reported key fusion loop (FL) residues and/or BC loop (BCL) residues on dengue virus (DENV) envelope protein acknowledged by flavivirus cross-reactive human monoclonal antibodies and polyclonal sera.
To enhance ZIKV serodiagnosis, we employed wild sort (WT) and FL or FL/BCL mutant virus-like particles (VLP) of ZIKV, DENV1 and West Nile virus (WNV) in enzyme linked immunosorbent assays (ELISA), and examined convalescent-phase serum or plasma samples from reverse-transcription PCR-confirmed circumstances with completely different ZIKV, DENV and WNV infections.
For IgG ELISA, ZIKV WT-VLP had a sensitivity of 100% and specificity of 52.9%, which was improved to 83.3% by FL/BCL mutant VLP and 92.2% by the ratio of relative optical density of mutant to WT VLP. Equally, DENV1 and WNV WT-VLP had a sensitivity/specificity of 100%/70.0% and 100%/56.3%, respectively; the specificity was improved to 93.3% and 83.0% by FL mutant VLP. For IgM ELISA, ZIKV, DENV1 and WNV WT-VLP had a specificity of 96.4%, 92.3% and 91.4%, respectively, for major an infection; the specificity was improved to 93.7 to 99.3% by FL or FL/BCL mutant VLP.
An algorithm based mostly on a mixture of mutant and WT-VLP IgG ELISA is proposed to discriminate major ZIKV, DENV and WNV infections in addition to secondary DENV and ZIKV an infection with earlier DENV infections; this might be a strong software to raised perceive the seroprevalence and pathogenesis of ZIKV in areas the place a number of flaviviruses co-circulate.
Elevated In Vitro Kinase Exercise in Peripheral Blood Mononuclear Cells of Leucine-Wealthy Repeat Kinase 2 G2019S Carriers: A Novel Enzyme-Linked Immunosorbent Assay-Primarily based Methodology
Background: Leucine-rich repeat kinase 2 kinase inhibitors are being vigorously pursued as potential therapeutic choices; nonetheless, there’s a essential want for delicate and quantitative assays of leucine-rich repeat kinase 2 perform and goal engagement.
Aims: Our goal was to check assortment and storage protocols for peripheral blood mononuclear cells, and to find out the optimum situations for downstream analyses of leucine-rich repeat kinase 2 in PD cohorts.
Strategies: Right here, we describe enzyme-linked immunosorbent assay-based assays able to detecting a number of points of leucine-rich repeat kinase 2 perform at endogenous ranges in human tissues.
Outcomes: In peripheral blood mononuclear cells from each wholesome and affected carriers of the G2019S mutation in leucine-rich repeat kinase 2, we report, for the primary time, considerably elevated in vitro kinase exercise, whereas detecting a important improve in pS935/leucine-rich repeat kinase 2 in idiopathic PD sufferers.
Description: A competitive ELISA for quantitative measurement of Rat Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rat Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Canine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Canine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Canine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse S100A8/S100A9 Heterodimer ELISA development kit
Description: For the development of sandwich ELISAs to measure natural and recombinant mouse S100 Calcium Binding Protein A8 and S100 Calcium Binding Protein A9 Heterodimer (S100A8/S100A9 Heterodimer). The Reagent Diluent recommended may be suitable for most cell culture supernate, serum, and plasma samples. The Reagent Diluent selected for use can alter the performance of an immunoassay. Reagent Diluent optimization for samples with complex matrices such as serum and plasma, may improve their performance in this assay. This kit contains sufficient materials to run ELISAs on at least five 96 well plates, provided the following conditions are met: • The reagents are prepared as described in this package insert. • The assay is run as described in the General ELISA Protocol. • The recommended microplates, buffers, diluents, substrates, and solutions are used. This package insert must be read in its entirety before using this product. Refer to the Certificate of Analysis for component concentrations as they may vary. For research use only. Not for use in diagnostic procedures.
Human S100A8/S100A9 Heterodimer ELISA development kit
Description: For the development of sandwich ELISAs to measure natural and recombinant human S100 Calcium Binding Protein A8/S100 Calcium Binding Protein A9 (S100A8/S100A9 Heterodimer). The Reagent Diluent recommended may be suitable for most cell culture supernate, serum, plasma, saliva, human milk, urine, and fecal samples. The Reagent Diluent selected for use can alter the performance of an immunoassay. Reagent Diluent optimization for samples with complex matrices such as serum, plasma, saliva, human milk, urine, and feces, may improve their performance in this assay. This kit contains sufficient materials to run ELISAs on at least five 96 well plates, provided the following conditions are met: • The reagents are prepared as described in this package insert. • The assay is run as described in the General ELISA Protocol. • The recommended microplates, buffers, diluents, substrates, and solutions are used. *This package insert must be read in its entirety before using this product. Refer to the Certificate of Analysis for component concentrations as they may vary. For research use only. Not for use in diagnostic procedures.
Description: A competitive ELISA for quantitative measurement of Goat Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Goat Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Goat Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Embryonic Ectoderm Development (EED) ELISA Kit
Description: A competitive ELISA for quantitative measurement of Guinea pig Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Embryonic Ectoderm Development ELISA kit
Description: A competitive ELISA for quantitative measurement of Guinea pig Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Embryonic Ectoderm Development ELISA kit
Description: A competitive ELISA for quantitative measurement of Guinea pig Embryonic Ectoderm Development in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Chicken Embryonic Ectoderm Development (EED) ELISA Kit
Description: A sandwich ELISA kit for quantitative measurement of Rat EED (Embryonic Ectoderm Development) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Mouse EED (Embryonic Ectoderm Development)
Description: A sandwich ELISA kit for quantitative measurement of Mouse EED (Embryonic Ectoderm Development) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Human EED (Embryonic Ectoderm Development)
Description: A sandwich ELISA kit for quantitative measurement of Human EED (Embryonic Ectoderm Development) in samples from Serum, Plasma, Cell supernatant
Rat Craniofacial Development Protein 1 (CFDP1) ELISA Kit
Description: A sandwich ELISA for quantitative measurement of Rat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Rat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Rat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Canine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Canine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Canine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Porcine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Porcine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Porcine Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Goat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Goat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Goat Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Mesoderm development candidate 1, Mesdc1 ELISA KIT
Description: A sandwich ELISA for quantitative measurement of Human Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Human Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Human Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Mouse Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Mouse Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Mouse Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Craniofacial development protein 1, CFDP1 ELISA KIT
Description: A sandwich ELISA for quantitative measurement of Rabbit Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Rabbit Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Rabbit Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Monkey Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Monkey Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Monkey Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Bovine Craniofacial development protein 2, CFDP2 ELISA KIT
Description: Quantitative sandwich ELISA for measuring Mouse Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Mesoderm development candidate 1 (MESDC1)
Description: Quantitative sandwich ELISA for measuring Mouse Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Mesoderm development candidate 1 (MESDC1)
Description: Quantitative sandwich ELISA for measuring Mouse Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Mesoderm development candidate 1 (MESDC1)
Description: Quantitative sandwich ELISA for measuring Human Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Mesoderm development candidate 1 (MESDC1)
Description: Quantitative sandwich ELISA for measuring Human Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Mesoderm development candidate 1 (MESDC1)
Description: Quantitative sandwich ELISA for measuring Human Mesoderm development candidate 1 (MESDC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Guinea pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Guinea pig Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Guinea pig Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Craniofacial development protein 1(CFDP1) ELISA kit
Description: A sandwich ELISA for quantitative measurement of Guinea pig Craniofacial development protein 1(CFDP1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
CFDP1 ELISA Kit| Bovine Craniofacial development protein 1 ELIS
Canine heartworm and warmth remedy: An analysis utilizing a effectively based mostly enzyme-linked immunosorbent assay (ELISA) and canine sera with confirmed heartworm an infection standing
Warmth remedy of serum has demonstrated improved detection of Dirofilaria immitis antigen in sera of sheltered canine with out figuring out the true an infection standing of the animals and in canine confirmed experimentally to be contaminated with heartworm.
Using archived sera with necropsy confirmed heartworm an infection standing (n = 665) and a micro-titer effectively based mostly ELISA antigen assay, this research evaluated how the composition of heartworm infections impacts antigen check outcomes pre- and post-heat remedy, decided subsequent adjustments to the antigen check sensitivity and specificity, and utility of optical density values.
The composition of heartworm infections current in canine with sera initially testing antigen unfavourable consisted of infections by lifeless 1/34 (2.9 %), immature 10/34 (29.4 %), male solely 7/34 (20.6 %), feminine solely 5/34 (14.7 %), and combined intercourse infections 11/34 (32.4 %) with 2-62 heartworms of which 6 had been microfilaremic. The composition of heartworm infections remaining antigen unfavourable post-heat remedy consisted of infections by lifeless 1/14 (7.1 %), immature 9/14 (64.3 %), male solely 2/14 (14.3 %), and combined intercourse infections 2/14 (14.3 %) with 6 and 62 heartworms of which 1 was microfilaremic.
The general sensitivity for all infections, mature heartworms, and mature females earlier than warmth remedy had been 86.9 %, 90.7 %, and 93.3 % and after warmth remedy sensitivity elevated to 94.6 %, 98.4 %, and 99.2 % respectively. A lower in specificity from 97.8%-96.1% was noticed following warmth remedy of heartworm unfavourable sera. Optical density values for the various an infection intensities current on this research clearly point out that consequence depth shouldn’t be reflective of the variety of heartworms current.
This research gives extra context for deciphering post-heat antigen outcomes for canine originating from animal shelters, demonstrates diagnostic utility of optical density, and highlights the necessity for improved heartworm diagnostics.
MicroTools Starter Kit #2
20 tools on 25mm rods (T2-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)
Magnetic push button wand (M-R-1013198)
Serrated-end tweezers (TW-1)
Holder and case with a tool location placard
Description: MicroTools Starter Kit #220 tools on 25mm rods (T2-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)Magnetic push button wand (M-R-1013198)Serrated-end tweezers (TW-1)Holder and case with a tool location placard
MicroTools Starter Kit #3
20 tools on 25mm rods (T3-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)
Magnetic push button wand (M-R-1013198)
Serrated-end tweezers (TW-1)
Holder and case with a tool location placard
Description: MicroTools Starter Kit #320 tools on 25mm rods (T3-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)Magnetic push button wand (M-R-1013198)Serrated-end tweezers (TW-1)Holder and case with a tool location placard
MicroTools Starter Kit #1
Contains:
20 tools on 25mm rods (T1-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)
Magnetic push button wand (M-R-1013198)
Serrated-end tweezers (TW-1)
Holder and case with a tool location placard
Description: MicroTools Starter Kit #1Contains:20 tools on 25mm rods (T1-L25-A1) preloaded into B1A-R resuable bases (GB-B1A-R-20)Magnetic push button wand (M-R-1013198)Serrated-end tweezers (TW-1)Holder and case with a tool location placard
Description: Description of target: Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF-mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysines of histones to the acetylases. The predominant target for inhibition is histone H4. HAT inhibition leads to silencing of HAT-dependent transcription and prevents active demethylation of DNA. Both isoforms stimulate DNA replication of the adenovirus genome complexed with viral core proteins; however, isoform 2 specific activity is higher.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.176 ng/mL
Cryo-EM Advanced Lab Tool Kit
Contains:
2 Quantifoil R 1.2/1.3 Copper 300 Mesh, 100 pack (M-CEM-Q3100CR1.3)
1 UltrAuFoil R 1.2/1.3 Gold Mesh 300, 50 pack (M-CEM-Q350AR13A)
1 Formvar Film on Copper Grid, 300 Mesh, 50 pack (M-CEM-FF300-Cu)
1 Grid-Stick
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Protein SET in samples from serum, plasma, tissue homogenates and other biological fluids.
Rabbit Anti-Rat Toolan's H1 parvovirus (THV) capsid protein VP2 antiserum
Description: UniPuck Starter Kit 3 x 214 Universal V1-Pucks (M-CP-111-021-7) with FREE Custom Engraving and FREE (M-CP-CENGR) custom color choice (M-CP-CustomColors)2 Cane Lifting J-Hooks (included in M-CP-111-065)2 Puck Wands (M-CP-111-026)2 Puck Separator Tools (M-CP-111-028)2 Puck Dewar Loading Tools (M-CP-111-027)2 Bent Cryo Tongs (M-CP-111-030)2 Double Puck Loading Dewars with Lids (M-CP-111-022)2 CX100 Dry Shipper (TW-CX100)2 NEW Upright Shipping Case (TW-4LSC) ** 2 Crystal Harvesting Sampler Kit 2 (MSK-2)240 B3S reusable bases (GB-B3S-R-240) * (* Can be substituted for another base style upon request)(**Previously contained TW-CX10-8C00 Shipping case which is being phased out)
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