ELISA Reagent

Description: Quantitativesandwich ELISA kit for measuring Human Myocilin(MYOC) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Description: A sandwich quantitative ELISA assay kit for detection of Human Myocilin (MYOC) in samples from tissue homogenates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Myocilin (MYOC) in samples from tissue homogenates or other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Myocilin (MYOC) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Myocilin (MYOC) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Myocilin (MYOC) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Myocilin (MYOC) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Myocilin (MYOC) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: tissue homogenates and other biological fluids.

Description: tissue homogenates and other biological fluids.

Description: tissue homogenates and other biological fluids.

Description: tissue homogenates and other biological fluids.

Description: A sandwich ELISA kit for detection of Myocilin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Mouse Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Mouse Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Mouse Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Bovine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Bovine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Bovine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Canine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Canine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Canine Myocilin (MYOC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Recombinant Human Myocilin expressed in: E.coli

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC)

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human Myocilin (MYOC). This antibody is labeled with APC-Cy7.

Description: A Monoclonal antibody against Human MYOC / Myocilin (clone 4F8). The antibodies are raised in Mouse and are from clone 4F8. This antibody is applicable in WB and IHC-P, E, RNAi

Description: Antibody raised against Myocilin

Description: Human Myocilin (MYOC) protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_000252)

Description: Human Myocilin (MYOC) protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_000252)

Description: Description of target: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.By similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More…</a></p> Manual assertion inferred from sequence similarity toiUniProtKB:O70624 (MYOC_MOUSE)8 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.24"Mitochondrial association of myocilin, product of a glaucoma gene, in human trabecular meshwork cells."_x005F_x005F_x000D_Sakai H., Shen X., Koga T., Park B.C., Noskina Y., Tibudan M., Yue B.Y._x005F_x005F_x000D_J. Cell. Physiol. 213:775-784(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN MITOCHONDRIAL DEPOLARIZATION, SUBCELLULAR LOCATION.Ref.25"Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells."_x005F_x005F_x000D_Shen X., Koga T., Park B.C., SundarRaj N., Yue B.Y._x005F_x005F_x000D_J. Biol. Chem. 283:603-612(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN CELL-MATRIX ADHESION.Ref.26"Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells."_x005F_x005F_x000D_Goldwich A., Scholz M., Tamm E.R._x005F_x005F_x000D_Histochem. Cell Biol. 131:167-180(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN CELL ADHESION.Ref.27"Myocilin is a modulator of Wnt signaling."_x005F_x005F_x000D_Kwon H.S., Lee H.S., Ji Y., Rubin J.S., Tomarev S.I._x005F_x005F_x000D_Mol. Cell. Biol. 29:2139-2154(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN STRESS FIBER ASSEMBLY, INTERACTION WITH FRZB; FZD7; FZD10; FZD1 AND WIF1, CHARACTERIZATION OF VARIANT ASN-477.Ref.28"Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth."_x005F_x005F_x000D_Koga T., Shen X., Park J.S., Qiu Y., Park B.C., Shyam R., Yue B.Y._x005F_x005F_x000D_Am. J. Pathol. 176:343-352(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN NEURITE OUTGROWTH.Ref.29"Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathway."_x005F_x005F_x000D_Kwon H.S., Tomarev S.I._x005F_x005F_x000D_J. Cell. Physiol. 226:3392-3402(2011) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN CELL MIGRATION.Ref.30"Myocilin stimulates osteogenic differentiation of mesenchymal stem cells through mitogen-activated protein kinase signaling."_x005F_x005F_x000D_Kwon H.S., Johnson T.V., Tomarev S.I._x005F_x005F_x000D_J. Biol. Chem. 288:16882-16894(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN OSTEOBLAST DIFFERENTIATION.Ref.31"Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling."_x005F_x005F_x000D_Kwon H.S., Johnson T.V., Joe M.K., Abu-Asab M., Zhang J., Chan C.C., Tomarev S.I._x005F_x005F_x000D_J. Biol. Chem. 288:26357-26371(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION IN MYELINATION, INTERACTION WITH NFASC; GLDN AND NRCAM. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.26 ng/mL

Description: Rabbit polyclonal MYOC antibody

Description: A polyclonal antibody against MYOC. Recognizes MYOC from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Description: A polyclonal antibody against MYOC. Recognizes MYOC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Description: Quantitative sandwich ELISA for measuring Human Myocardin (MYOCD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myocardin (MYOCD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myocardin (MYOCD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A cloning plasmid for the MYOC gene.

Description: A polyclonal antibody for detection of MYOC from Human, Mouse, Rat. This MYOC antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human MYOC protein

Description: A polyclonal antibody for detection of MYOC from Human, Mouse, Rat. This MYOC antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human MYOC protein

Description: A polyclonal antibody for detection of MYOC from Human, Mouse, Rat. This MYOC antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human MYOC protein

Description: A Rabbit Polyclonal antibody against MYOC from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against MYOC from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A sandwich ELISA for quantitative measurement of Human Myocardin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Human Myocardin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Human Myocardin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A polyclonal antibody against MYOC. Recognizes MYOC from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against MYOC. Recognizes MYOC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Description: Quantitative sandwich ELISA for measuring Human Myosin-Vc (MYO5C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myosin-Vc (MYO5C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myosin-Vc (MYO5C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myosin-Ic (MYO1C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myosin-Ic (MYO1C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Myosin-Ic (MYO1C) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A polyclonal antibody against MYOC. Recognizes MYOC from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Description: Description of target: This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.083 ng/mL

Description: Quantitative sandwich ELISA for measuring Rat Myocardin (MYOCD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Myocardin (MYOCD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.